At Roche, you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted, and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop, and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position We advance science so that we all have more time with the people we love. Roche Diagnostics acquired Stratos Genomics in 2020 for its unique chemistry that advances DNA sequencing by nanopore, Sequencing by Expansion (SBX). You will engineer and synthesize the molecular building blocks for our novel technology. These building blocks translate DNA sequences into a simple to measure surrogate, the Xpandomer, which significantly improves the accuracy and throughput of nanopore sequencing. The Molecular Engineering group is passionate about the novel molecules they have developed and the impact SBX technology can have on advancing sequencing and patient outcomes. We are looking for people who are excited about the significance of our technology and want to make SBX successful. The Opportunity: Research, design, and execute innovative and well-controlled experiments, with high attention to detail. Lead, mentor, and drive cross-functional teams. Identify and troubleshoot problems in creative ways. Contribute to the definition and timely achievement of project goals. Develop SOPs to aid in the production of reagents and starting materials. Participate in the production of reagents and starting materials. Perform data analysis and protocol development. Maintain accurate, detailed, and reliable laboratory records. Present findings at group or departmental meetings. Maintain the lab's cleanliness and organization. Develop and propose improved processes to fulfill the above functions. Who You Are: You have 6 years of laboratory experience in advanced nucleotide/heterocyclic chemistry, phosphorus chemistry, and/or complex/multi-step organic synthesis. You have a Bachelor's degree in Organic Synthesis, Chemistry, Chemical Engineering, Biochemistry, or a related field, and 8 years of experience, or a Master's degree in the same fields with 7 years of experience, or a PhD in the same fields with 4 years of experience. Ideally, you will have: Demonstrated ability to understand and develop chemistry for: Nucleotides Phosphoramidites Heterocycles Amino Acids Bio-conjugations Mature understanding of how to work with chemical and biochemical samples, including sample handling, reactivity, purification, and storage. Technical background in next-generation DNA sequencing. Experience with HPLC, MS, NMR, automated DNA synthesizers, inert atmosphere chambers, and manual pipetting. Application instructions: Include a cover letter addressing: Clearly state your motivation for wanting to work with us. Describe your specific technical interest in SBX technology and how you envision contributing. Outline potential challenges related to the molecular engineering of SBX technology and propose solutions. Submitting a comprehensive cover letter that addresses these points is necessary. Relocation benefits are available. The expected salary range for Seattle, WA is $94,200 - $175,000. Actual pay will be based on experience, qualifications, geographic location, and other factors. A discretionary annual bonus may also be available. This position qualifies for the benefits detailed here: Benefits Relocation benefits are available. Who we are A healthier future drives us to innovate. Over 100,000 employees worldwide are dedicated to advancing science, ensuring access to healthcare today and for future generations. Our efforts have resulted in over 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep high ambitions to deliver life-changing healthcare solutions with a global impact. Let's build a healthier future, together. Roche is an equal opportunity employer. It is our policy to employ, promote, and treat all employees and applicants based on merit, qualifications, and competence. Discrimination based on protected veteran status, disability, or other protected categories is prohibited. If you need accommodations for the online application process, please contact us through the Accommodations for Applicants form. #J-18808-Ljbffr Roche Holdings Inc.
...Value & Variety Mobil in Gallatin, TN is looking for one pizza hut crew member to join our 13 person strong team. We are located on 501 Garnet Ct. Our ideal candidate is attentive, motivated, and reliable. By applying to this job, you agree to receive periodic text...
About The Durable Slate Company The Durable Slate Company is an award-winning slate roofing company serving the Eastern United States, with offices located throughout Ohio and Maryland. Founded in 1986, The Durable Slate Company provides premium historic roofing services...
...ensuring the smooth flow of traffic across the scale. Assists in the coordination of truck... ...orders received from Dispatch Office and operates computer to produce appropriate customer... ...housekeeping duties to ensure that scale house is clean and orderly. Assists Plant...
...The Excalibur Group is currently seeking a Court Reporter in Washington, DC to support a Federal contract. **Must be able to pass a security screening. SUMMARY As a trained Court Reporter, you will use specialized equipment for creating and maintaining accurate...
The OpportunityBOX CLEVERINDUSTRIAL DESIGN INTERN. 4 to 6 MONTHS. Start May/June, 2025We are Box Clever, a design studio that creates highly impactful products, brands, & businesses. Recognized as one of the Top 10 Most Innovative Design Companies by Fast Company...